FAQ: Wellbutrin and LDN for Weight Loss


How does Wellbutrin plus LDN help with weight loss?
Wellbutrin (bupropion) and low dose naltrexone (LDN) affect brain chemicals linked to appetite and impulse control. Together, they may help curb cravings, reduce binge eating, and support weight loss for some people.
Can these medications help with emotional eating?
Yes, both medications can help address the emotional side of overeating. Wellbutrin can lift mood and boost motivation, which may make you less likely to eat for comfort. LDN may help reduce reward-seeking behavior, so you're less tempted to eat for emotional reasons.
Who might be a good fit for Wellbutrin and LDN for weight loss?
You might be a good candidate if you often feel out of control with food, struggle with binge eating, or eat when you’re upset. People who have trouble with emotional eating or frequent overeating may benefit most.
How long does it take for Wellbutrin and LDN to start working?
Some people may notice changes in appetite or mood within the first two weeks. It can take up to six weeks to feel the full effects, especially for help with emotional eating.
Can these medications help with other conditions too?
Yes, Wellbutrin also treats depression and can boost energy, drive, and focus. It sometimes helps people with ADHD-type symptoms or seasonal affective disorder. LDN shows promise for chronic pain, autoimmune problems, and sometimes improves mood.
What side effects could I have with Wellbutrin and LDN?
You might have trouble sleeping, dry mouth, headache, or mild nausea. Some people feel more anxious or jittery at first. Rarely, Wellbutrin can cause serious side effects like seizures, especially at higher doses.
Who shouldn’t try Wellbutrin and LDN for weight loss?
These aren’t good choices if you’ve had seizures, an eating disorder like bulimia, or heavy alcohol use. People taking certain other medications (like MAOIs or opioids) should avoid them. Always check with your provider about your full medical history.
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